IL16 Antikörper (N-Term)

Produktnummer ABIN499976

Der Kaninchen Polyklonal Anti-IL16-Antikörper wurde für WB und EIA validiert. Er ist geeignet, IL16 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für IL16 Antikörper (N-Term) (ABIN499976)

Target: IL16 (Interleukin 16 (IL16))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-IL16 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to IL-16.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: IL-16 antibody was raised against a 14 amino acid peptide near the amino terminus of human IL-16.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu IL16

Target: IL16 (Interleukin 16 (IL16))

Andere Bezeichnung: Interleukin-16 / IL16

Hintergrund: IL-16 was initially identified as a chemotactic cytokine, but is now known to possess a wide range of activities. Later studies have more fully characterized IL-16 as an immunomodulatory cytokine that contributes to the regulatory process of CD4+ T cell recruitment and activation at sites of inflammation in association with asthma and several autoimmune diseases. The precursor of IL-16 (pro-IL-16) is thought to be cleaved towards the C-terminal region by Caspase-3, releasing a 20 kDa active form that binds to and signals through CD4. Besides acting as a chemotactic cytokine, IL-16 is thought to also be involved in the regulation of T cell proliferation and multiple infectious, immune-mediated, and autoimmune inflammatory disorders including irritable bowel syndrome, systemic lupus erythematosus, and neurodegenerative disorders. At least two isoforms of IL-16 are known to exist, the longer isoform (also known as NIL-16) is detected only in neurons of the cerebellum and hippocampus. This antibody will only detect the NIL-16 isoform.Synonyms: IL-16, LCF, Lymphocyte chemoattractant factor

Gen-ID: 3603

NCBI Accession: NP_004504

UniProt: Q14005