ACBD3 Antikörper (N-Term)

Produktnummer ABIN499900

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ACBD3 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ACBD3 Antikörper (N-Term) (ABIN499900)

Target: ACBD3 (Acbd3) (Acyl-CoA Binding Domain Containing 3 (Acbd3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACBD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-ACBD3 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: GOLPH1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human GOLPH1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu ACBD3

Target: ACBD3 (Acbd3) (Acyl-CoA Binding Domain Containing 3 (Acbd3))

Andere Bezeichnung: ACBD3

Hintergrund: GOLPH1, also known as GCP60, was initially identified as a Golgi protein that can interact with the integral membrane protein giantin and is thought to be involved in the maintenance of the Golgi structure. GOLPH1 has also been shown to interact with other Golgi proteins such as Golgin-160, a Golgi protein that can be cleaved by caspases-2, -3, and -7, leading to the nuclear localization of Golgin-160. GOLPH1 interaction with the Golgin-160 fragments is stronger than that with the intact Golgin-160, with its interaction regulated by the oxidation state of Cys-463 within GOLPH1, suggesting that the nuclear localization of the caspase-cleaved Golgin-160 fragments is a highly coordinated event. GOLPH1 has also been found to interact with Numb, a cytosolic signaling protein that mediates asymetric cell division of neural progenitor cells to a daughter progenitor cell and a neuron, suggesting that Golgi fragmentation and reconstitution during the cell cycle differentially regulate Numb signaling through changes in GOLPH1 subcellular distribution and may couple cell fate with cell cycle progression.Synonyms: Acyl-CoA-binding domain-containing protein 3, GOCAP1, GOLPH1, Golgi complex-associated protein 1, Golgi phosphoprotein 1, Golgi resident protein GCP60, PAP7, PBR- and PKA-associated protein 7, Peripheral benzodiazepine receptor-associated protein

Gen-ID: 64746

NCBI Accession: NP_073572

UniProt: Q9H3P7