GDF6 Antikörper (C-Term)

Produktnummer ABIN499881

Dieses Anti-GDF6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GDF6 in WB und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für GDF6 Antikörper (C-Term) (ABIN499881)

Target: GDF6 (Growth Differentiation Factor 6 (GDF6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GDF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-GDF6 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to GDF6.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: GDF6 antibody was raised against a 17 amino acid peptide near the carboxy terminus of the human GDF6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu GDF6

Target: GDF6 (Growth Differentiation Factor 6 (GDF6))

Andere Bezeichnung: BMP13 / GDF6

Hintergrund: Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. Both GDF6 and GDF7 are closely related to GDF5 which has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. In Xenopus, GDF6 is expressed at the edge of the neural plate and within the anterior neural plate including the eye fields. GDF6 is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. It may regulate patterning of the ectoderm by interacting with bone morphogenetic proteins (BMPs), and control eye development. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), a congenital disorder of spinal segmentation.Synonyms: Bone Morphogenetic Protein 13, CDMP2, Cartilage Derived Morphogenetic Protein 2, GDF-16, GDF-6, GDF16

Gen-ID: 392255

NCBI Accession: NP_001001557

UniProt: Q6KF10