FTO Antikörper (N-Term)

Produktnummer ABIN499863

Dieses Anti-FTO-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FTO in WB, IHC (p) und EIA. Geeignet für Human.

Kurzübersicht für FTO Antikörper (N-Term) (ABIN499863)

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FTO Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-FTO Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to FTO.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: FTO antibody was raised against a 15 amino acid peptide from near the amino terminus of human FTO.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu FTO

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Andere Bezeichnung: FTO

Hintergrund: Rising obesity rates are rapidly becoming a growing health concern in the developing world. The fat mass and obesity associated gene (FTO) is the first gene discovered to contribute to common forms of human obesity. FTO is a member of the non-heme dioxygenase superfamily, encoding a 2-oxoglutarate-dependent nucleic acid demethylase whose mRNA is widely expressed, especially in neurons of feeding-related nuclei of the brain. FTO mRNA in the arcuate nucleus in mice is up-regulated by feeding and down-regulated during fasting, although the opposite pattern has been observed in rats. At least four isoforms of FTO are known to exist.Synonyms: Fat mass and obesity-associated protein, KIAA1752

Gen-ID: 79068

UniProt: Q9C0B1