FKBP15 Antikörper (N-Term)

Produktnummer ABIN499840

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FKBP15 in WB, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für FKBP15 Antikörper (N-Term) (ABIN499840)

Target: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-FKBP15 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to FKBP15.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: FKBP15 antibody was raised against a 15 amino acid peptide from near the amino terminus of human FKBP15.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu FKBP15

Target: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Andere Bezeichnung: FKBP15

Hintergrund: FKBP15, also known as FKBP133, is a member of the FK506-binding protein family, a group of proteins initially identified as immunophilins, targets for the immunosupressant drugs FK506 and Rapamycin. FKBP15 is expressed in the developing nervous system and contains a domain similar to Wiskott-Aldrich syndrome protein homology region 1 (WH1) in addition to the FK506-binding protein motif. FKBP15 is distributed along the axonal shafts and partially co-localizes with F-actin in the growth cones of dorsal root ganglion neurons, overexpression of FKBP15 resulted in the number of filopodia in transfected neurons, suggesting that FKBP15 modulates growth cone behavior. FKBP15 has also been shown to associate with both microtubules and the actin filament systems and disruption of its expression by RNAi resulted in delayed transport of early endosomes in HeLa cells indicating that FKBP15 is also involved in the transport of early endosomes. At least three isoforms of FKBP15 are known to exist.Synonyms: 133 kDa FK506-binding protein, FK506-binding protein 15, FKBP133, KIAA0674, WAFL, WASP and FKBP-like

Gen-ID: 23307

NCBI Accession: NP_056073

UniProt: Q5T1M5

Pathways: SARS-CoV-2 Protein Interaktom