FAIM Antikörper (C-Term)

Produktnummer ABIN499820

Produktdetails anti-FAIM Antikörper

Target: FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAIM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to FAIM.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: FAIM antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human FAIM.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu FAIM

Target: FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))

Andere Bezeichnung: FAIM (FAIM Produkte)

Synonyme: FAIM1 antikoerper, FAIM antikoerper, faim antikoerper, zgc:92712 antikoerper, zgc:92723 antikoerper, Fas apoptotic inhibitory molecule antikoerper, Fas apoptotic inhibitory molecule L homeolog antikoerper, Fas apoptotic inhibitory molecule b antikoerper, Fas apoptotic inhibitory molecule a antikoerper, FAIM antikoerper, Faim antikoerper, faim antikoerper, faim.L antikoerper, Tsp_00038 antikoerper, faimb antikoerper, faima antikoerper

Hintergrund: The susceptibility of primary splenic B cells to Fas-mediated apoptosis is regulated in a receptor-specific fashion. Terminal effectors of B cell Fas-resistance include the known anti-apoptotic proteins Bcl-xL, FLIP, and a recently identified protein termed FAIM. This molecule is broadly expressed in various tissues and exists in at least three isoforms. It is thought that resistance to Fas killing via increased expression of FAIM protects foreign antigen-specific B cells during interactions with FasL-bearing T cells whereas autoreactive B cells are deleted via Fas-dependent cytotoxicity. More recent results have indicated that FAIM interacts with both Trk and p75 neurotrophin receptor and may play a role in promoting neurite outgrowth in different neuronal systems by a mechanism involving the activation of NF-kappaB and the Ras-ERK pathway.Synonyms: FAIM-1, FAIM1, Fas Apoptotic Inhibitory Molecule 1

Gen-ID: 55179

NCBI Accession: NP_060617

UniProt: Q9NVQ4