Emerin Antikörper (N-Term)

Produktnummer ABIN499790

Der Kaninchen Polyklonal Anti-Emerin-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, Emerin in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Emerin Antikörper (N-Term) (ABIN499790)

Target: Emerin (EMD)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Emerin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-Emerin Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to Emerin.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Emerin antibody was raised against a 19 amino acid peptide from near the amino terminus of human Emerin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Emerin

Target: Emerin (EMD)

Andere Bezeichnung: Emerin

Hintergrund: Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family that includes proteins such as LAP2 and MAN1. Each family member, including Emerin, has an ~40 amino acid LEM-domains that binds barrier-to-autointegration (BANF1), a conserved chromatin protein that also serves as a host cell component of retroviral integration complexes, including that of HIV. Emerin is anchored at the inner membrane of the nuclear envelope where it binds to nuclear intermediate filaments that are formed by lamin proteins. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.Synonyms: EDMD, EMD, STA

Gen-ID: 2010

NCBI Accession: NP_000108

UniProt: P50402