EFHD2 Antikörper (N-Term)

Produktnummer ABIN499784

Der Kaninchen Polyklonal Anti-EFHD2-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, EFHD2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für EFHD2 Antikörper (N-Term) (ABIN499784)

Target: EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EFHD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-EFHD2 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: EFHD2 antibody was raised against a 16 amino acid peptide near the amino terminus of human EFHD2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: EFHD2 antibody can be used for detection of EFHD2 by Western blot at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu EFHD2

Target: EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))

Andere Bezeichnung: EFHD2

Hintergrund: EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLCgamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-kappa-B-activating branch.Synonyms: EF-hand domain-containing protein D2, SWS1, Swiprosin 1, Swiprosin-1

Gen-ID: 79180

NCBI Accession: NP_077305

UniProt: Q96C19