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DRAK2 Antikörper (C-Term)

This anti-DRAK2 antibody (ABIN499770) is a Rabbit Polyclonal antibody detecting DRAK2 in WB, IF, EIA. Suitable for Human.
Produktnummer ABIN499770

Kurzübersicht für DRAK2 Antikörper (C-Term) (ABIN499770)

Target

Alle DRAK2 (STK17B) Antikörper anzeigen
DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))

Reaktivität

  • 38
  • 16
  • 8
  • 1
  • 1
  • 1
Human

Wirt

  • 35
  • 2
  • 1
Kaninchen

Klonalität

  • 37
  • 1
Polyklonal

Konjugat

  • 22
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DRAK2 Antikörper ist unkonjugiert

Applikation

  • 26
  • 21
  • 9
  • 3
  • 3
  • 3
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 7
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Spezifität

    DRAK2 antibody was raised against a peptide corresponding to amino acids 351 to 365 of human DRAK2. It has no cross responses to DAP or ZIP kinases.

    Aufreinigung

    Ion exchange chromatography

    Immunogen

    Human DRAK2 (C-Terminus) Peptide

    Isotyp

    IgG
  • Applikationshinweise

    ELISA. Western Blot: 1/500 to 1/1000. An approximately 45 kDa band can be detected. Theapproximately 70 kDa band is probably non-related to DRAK2 although it is peptideblockable. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C.
  • Target

    DRAK2 (STK17B) (serine/threonine Kinase 17b (STK17B))

    Andere Bezeichnung

    STK17B / DRAK2

    Hintergrund

    Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase-related apoptosis-inducing protein kinases) (1). DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues (1).Synonyms: DAP kinase-related apoptosis-inducing protein kinase 2, Serine/threonine-protein kinase 17B

    Gen-ID

    9262

    UniProt

    O94768
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