DCLK3 Antikörper (N-Term)

Produktnummer ABIN499720

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DCLK3 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für DCLK3 Antikörper (N-Term) (ABIN499720)

Target: DCLK3 (Doublecortin-Like Kinase 3 (DCLK3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCLK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-DCLK3 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: DCLK3 antibody was raised against a 14 amino acid peptide near the amino terminus of human DCLK3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1 - 2 μg/mL. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu DCLK3

Target: DCLK3 (Doublecortin-Like Kinase 3 (DCLK3))

Andere Bezeichnung: Doublecortin-Like Kinase 3

Hintergrund: DCLK3 is one of three doublecortin-like kinases similar to the Ca2+/calmodulin-dependent protein kinase (CaMK) family. DCLK3 mRNA, like that of the homologous DCLK1 and DCLK3, is highly expressed in adult brain, but only DCLK3 transcripts are present in liver and kidney, suggesting that DCLK3 may play other roles than in cortical development. The DCLK proteins are homologous to Doublecortin (DCX), a protein that is mutated in X-linked human lissencephaly. In mouse models where the DCX gene has been disrupted, DCLK1 expression increases slightly and appears to compensate for the loss of DCX, as mice mutant for both DCX and DCLK1 show a severe phenotype including perinatal lethality, disorganized neocortical layering, and profound hippocampal cytoarchitectural disorganization.Synonyms: DCAMKL3, DCDC3C, DCK3, DCLK3, KIAA1765, Serine/threonine-protein kinase DCLK3

Gen-ID: 85443

NCBI Accession: NP_208382

UniProt: Q9C098