BAIAP2 Antikörper (AA 151-250) (AbBy Fluor® 750)
Quick Overview for BAIAP2 Antikörper (AA 151-250) (AbBy Fluor® 750) (ABIN4997180)
Target
Alle BAIAP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 151-250
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human IRS P53
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))
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Andere Bezeichnung
- BAIAP2
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Hintergrund
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Synonyms: Insulin receptor substrate P53, IRSp53, IRS P53, IRS-P53, Baiap2, BAI1 associated protein 2 isoform 3, Brain-specic angiogenesis inhibitor 1-associated protein 2, BAI1-associated protein 2, Insulin receptor tyrosine kinase substrate protein p53, Insulin receptor substrate p53, Insulin receptor substrate protein of 53 kDa, IRSp53, BAIP2_HUMAN, BAI-associated protein 2, BAI1-associated protein 2, Protein BAP2, Fas ligand-associated factor 3, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53 kDa, FLAF3, IRS-58, IRSp53/58.
Background: The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. Alternative splicing of the end of this gene results in three products of undetermined function.
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Gen-ID
- 10458
Target
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