DAXX Antikörper (C-Term)

Produktnummer ABIN499714

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DAXX in WB, IF und EIA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für DAXX Antikörper (C-Term) (ABIN499714)

Target: DAXX (Death-Domain Associated Protein (DAXX))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAXX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-DAXX Antikörper

Bindungsspezifität: C-Term

Spezifität: Daxx antibody was raised against a peptide corresponding to amino acids near the carboxy-terminus of human Daxx.

Aufreinigung: DEAE

Immunogen: Human Daxx (C-Terminus) Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1-2 μg/mL. A 120 kDa major band can be detected. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu DAXX

Target: DAXX (Death-Domain Associated Protein (DAXX))

Andere Bezeichnung: DAXX

Hintergrund: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. A novel DD-containing molecule was recently cloned from mouse, human and monkey and designated Daxx. Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway. Daxx is widely expressed in fetal and adult human and mouse tissues indicating its important function in Fas signaling pathways.Synonyms: BING2, DAP6, Death domain-associated protein 6, EAP1, ETS1-associated protein 1, Fas death domain-associated protein

Gen-ID: 1616

NCBI Accession: NP_001135441

UniProt: Q9UER7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway