C1QTNF4 Antikörper (N-Term)

Produktnummer ABIN499671

Der Kaninchen Polyklonal anti-C1QTNF4 Antikörper (ABIN499671) detektiert spezifisch C1QTNF4 in WB, IHC (p) und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für C1QTNF4 Antikörper (N-Term) (ABIN499671)

Target: C1QTNF4 (Complement C1q Tumor Necrosis Factor-Related Protein 4 (C1QTNF4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1QTNF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-C1QTNF4 Antikörper

Bindungsspezifität: N-Term

Spezifität: CTRP4 antibody was raised against a 16 amino acid peptide from near the center of human CTRP4.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Human CTRP4 (N-Terminus) Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: CTRP4 antibody can be used for the detection of CTRP4 at 1 - 2 μg/mL. Ratbrain cell lysate can be used as positive control. These proteins are often highly modifiedpost-translationally and migrate in SDS-PAGE at positions other than their predicted size. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu C1QTNF4

Target: C1QTNF4 (Complement C1q Tumor Necrosis Factor-Related Protein 4 (C1QTNF4))

Andere Bezeichnung: C1QTNF4

Hintergrund: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Multiple isoforms of mouse CTRP4 have been reported.Synonyms: CTRP4, Complement C1q tumor necrosis factor-related protein 4

Gen-ID: 114900

UniProt: Q9BXJ3