Apoptosis Inhibitor 5 Antikörper (AA 351-460) (AbBy Fluor® 680)
Kurzübersicht für Apoptosis Inhibitor 5 Antikörper (AA 351-460) (AbBy Fluor® 680) (ABIN4996668)
Target
Alle Apoptosis Inhibitor 5 (API5) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 351-460
-
Kreuzreaktivität
- Maus
-
Homologie
- Human,Rat,Dog,Cow,Pig,Horse,Guinea Pig
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human API5
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- FCM 1:20-100
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- Apoptosis Inhibitor 5 (API5)
-
Andere Bezeichnung
- API5
-
Hintergrund
-
Synonyms: AAC11, AAC-11, Apoptosis inhibitor 5, API-5, Antiapoptosis clone 11 protein, Cell migration-inducing gene 8 protein, Fibroblast growth factor 2-interacting factor, FIF, Protein XAGL, API5, MIG8
Background: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
-
Gen-ID
- 8539
-
UniProt
- Q9BZZ5
-
Pathways
- Growth Factor Binding
Target
-