CRMP1 Antikörper (Intermediate Domain)

Produktnummer ABIN499652

Der Kaninchen Polyklonal Anti-CRMP1-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, CRMP1 in Proben von Human und Maus zu detektieren.

Kurzübersicht für CRMP1 Antikörper (Intermediate Domain) (ABIN499652)

Target: CRMP1 (Collapsin Response Mediator Protein 1 (CRMP1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-CRMP1 Antikörper

Bindungsspezifität: Intermediate Domain

Spezifität: CRMP1 antibody was raised against a 16 amino acid peptide from near the center of human CRMP1.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Virus CRMP1 / Collapsin response mediator protein 1 / DRP-1 / dihydropyropyrimidinase- related protein 1 (Intermediate Domain) Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: CRMP1 antibody can be used for the detection of CRMP1 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu CRMP1

Target: CRMP1 (Collapsin Response Mediator Protein 1 (CRMP1))

Andere Bezeichnung: CRMP1 / DPYSL1

Hintergrund: Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis (1). Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity (2). CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain (3), later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth (4). CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons (5).Synonyms: Collapsin response mediator protein 1, DRP-1, Dihydropyrimidinase-related protein 1, ULIP3, Unc-33-like phosphoprotein 3

Gen-ID: 1400

UniProt: Q14194