CLIP1 Antikörper (C-Term)

Produktnummer ABIN499641

Dieses Anti-CLIP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CLIP1 in WB, IF und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für CLIP1 Antikörper (C-Term) (ABIN499641)

Target: CLIP1 (CAP-GLY Domain Containing Linker Protein 1 (CLIP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-CLIP1 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to CLIP170.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: CLIP170 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human CLIP170.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: CLIP170 antibody can be used for detection of CLIP170 at 0.5 - 1 μg/mL. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu CLIP1

Target: CLIP1 (CAP-GLY Domain Containing Linker Protein 1 (CLIP1))

Andere Bezeichnung: CLIP1 / Restin

Hintergrund: CLIP170 was initially identified as a new type of intermediate filament associated protein that is highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin's disease. Later experiments showed that it is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles. CLIP170 has also been suggested to act with LIS1, a protein implicated in brain development, to regulate dynein/dynactin binding microtubules. Other studies suggest that CLIP170 can influence the formation of lamellipodia and cell invasion by invasive breast cancer cells by regulating the release of kinesin and IQGAP1 from a complex of those proteins, CLIP170 and Rac1. At least two isoforms of CLIP170 are known to exist.Synonyms: CAP-Gly domain-containing linker protein 1, CLIP-170, CYLN1, Cytoplasmic linker protein 1, Cytoplasmic linker protein 170 alpha-2, RSN, Reed-Sternberg intermediate filament-associated protein

Gen-ID: 6249

NCBI Accession: NP_002947

UniProt: P30622

Pathways: Microtubule Dynamics