CCDC134 Antikörper (N-Term)

Produktnummer ABIN499587

Dieses Anti-CCDC134-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CCDC134 in WB, IHC (p) und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für CCDC134 Antikörper (N-Term) (ABIN499587)

Target: CCDC134 (Coiled-Coil Domain Containing 134 (CCDC134))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC134 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-CCDC134 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to CCDC134.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: CCDC134 antibody was raised against a 17 amino acid peptide near the amino terminus of human CCDC134.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: CCDC134 antibody can be used for detection of CCDC134 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu CCDC134

Target: CCDC134 (Coiled-Coil Domain Containing 134 (CCDC134))

Andere Bezeichnung: CCDC134

Hintergrund: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein. Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription. CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines.Synonyms: Coiled-coil domain-containing protein 134

Gen-ID: 79879

NCBI Accession: NP_079097

UniProt: Q9H6E4