Cathelicidin Antikörper (C-Term)

Produktnummer ABIN499581

Dieses Anti-Cathelicidin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cathelicidin in WB, IHC (p) und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Cathelicidin Antikörper (C-Term) (ABIN499581)

Target: Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathelicidin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-Cathelicidin Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects Cathelicidin.

Aufreinigung: Peptide Affinity Chromatography

Immunogen: Cathelicidin antibody was raised against a 17 amino acid peptide near the carboxy terminus of the Human Cathelicidin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: Cathelicidin antibody can be used for detection of Cathelicidin at 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Cathelicidin

Target: Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))

Andere Bezeichnung: CAMP / CAP18

Hintergrund: One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.Synonyms: 18 kDa cationic antimicrobial protein, Antibacterial protein LL-37, CAP-18, Cathelicidin antimicrobial peptide, FALL-39, FALL39, HSD26, hCAP-18

Gen-ID: 820

NCBI Accession: NP_004336

UniProt: P49913

Pathways: Cellular Response to Molecule of Bacterial Origin