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Calpain 6 Antikörper (C-Term)

Dieses Anti-Calpain 6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Calpain 6 in WB, IHC (p) und EIA. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN499521

Kurzübersicht für Calpain 6 Antikörper (C-Term) (ABIN499521)

Target

Alle Calpain 6 (CAPN6) Antikörper anzeigen
Calpain 6 (CAPN6)

Reaktivität

Human, Maus, Ratte

Wirt

  • 28
  • 4
Kaninchen

Klonalität

  • 28
  • 4
Polyklonal

Konjugat

  • 17
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Calpain 6 Antikörper ist unkonjugiert

Applikation

  • 22
  • 17
  • 16
  • 6
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    Spezifität

    This antibody reacts to CAPN6.

    Aufreinigung

    Affinity chromatography purified via peptide column

    Immunogen

    CAPN6 antibody was raised against a 18 amino acid peptide from near the carboxy terminus of human CAPN6.

    Isotyp

    IgG
  • Applikationshinweise

    ELISA. Western Blot: CAPN6 antibody can be used for the detection of StrepII at 0.5 - 1 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C.
  • Target

    Calpain 6 (CAPN6)

    Andere Bezeichnung

    Calpain-6

    Hintergrund

    Calpains make up a ubiquitously expressed, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. This large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes as their activation can be triggered by calcium influx and oxidative stress. Calpain 6 (CAPN6) is most similar to Calpain 5, the C-terminal region of CAPN6 lacks homology to the calmodulin-like domain of other vertebrate calpains. CAPN6 is thought to be involved in the regulation of microtubule dynamics and cytoskeletal organization. CAPN6 has also been recently identified as an HIV dependency factor (HDF), suggesting that CAPN6 may be an important drug target in HIV treatment.Synonyms: CALPM, CANPX, CAPN6, Calpain-like protease X-linked, Calpamodulin

    Gen-ID

    827

    NCBI Accession

    NP_055104

    UniProt

    Q9Y6Q1
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