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BFAR Antikörper (C-Term)

BFAR Reaktivität: Human, Maus, Ratte WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499449
  • Target Alle BFAR Antikörper anzeigen
    BFAR (Bifunctional Apoptosis Regulator (BFAR))
    Bindungsspezifität
    • 14
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 29
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 36
    • 1
    Kaninchen
    Klonalität
    • 36
    • 1
    Polyklonal
    Konjugat
    • 14
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BFAR Antikörper ist unkonjugiert
    Applikation
    • 25
    • 23
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    BFAR antibody was raised against a 14 amino acid peptide near the carboxy terminus of human BFAR.
    Isotyp
    IgG
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    Discover our top product BFAR Primärantikörper
  • Applikationshinweise
    ELISA. Western Blot: BFAR antibody can be used for detection of BFAR at 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C.
  • Target
    BFAR (Bifunctional Apoptosis Regulator (BFAR))
    Andere Bezeichnung
    BFAR / RNF47 (BFAR Produkte)
    Synonyme
    BFAR antikoerper, MGC137916 antikoerper, bfar antikoerper, BAR antikoerper, RNF47 antikoerper, 3010001A07Rik antikoerper, AI666707 antikoerper, AW107665 antikoerper, Bar antikoerper, Rnf47 antikoerper, bifunctional apoptosis regulator antikoerper, bifunctional apoptosis regulator L homeolog antikoerper, BFAR antikoerper, bfar.L antikoerper, bfar antikoerper, Bfar antikoerper
    Hintergrund
    The bifunctional apoptosis inhibitor (BFAR) is scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery. BFAR is a multidomain protein capable of inhibiting apoptosis induced by TNF-family death receptors (extrinsic pathway) as well as mitochondria-dependent apoptosis (intrinsic pathway). Interaction of BFAR with Bcl-2 or Bcl-XL via a SAM domain may contribute to the anti-apoptotic properties of BFAR. In addition, BFAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. BFAR is also thought to be involved in the regulation of neuronal survival.Synonyms: BAR, Bifunctional apoptosis regulator, RING finger protein 47
    Gen-ID
    51283
    NCBI Accession
    NP_057645
    UniProt
    Q9NZS9
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