BFAR Antikörper (C-Term)

Produktnummer ABIN499449

Dieses Anti-BFAR-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BFAR in WB und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für BFAR Antikörper (C-Term) (ABIN499449)

Target: BFAR (Bifunctional Apoptosis Regulator (BFAR))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BFAR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-BFAR Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: BFAR antibody was raised against a 14 amino acid peptide near the carboxy terminus of human BFAR.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: BFAR antibody can be used for detection of BFAR at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu BFAR

Target: BFAR (Bifunctional Apoptosis Regulator (BFAR))

Andere Bezeichnung: BFAR / RNF47

Hintergrund: The bifunctional apoptosis inhibitor (BFAR) is scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery. BFAR is a multidomain protein capable of inhibiting apoptosis induced by TNF-family death receptors (extrinsic pathway) as well as mitochondria-dependent apoptosis (intrinsic pathway). Interaction of BFAR with Bcl-2 or Bcl-XL via a SAM domain may contribute to the anti-apoptotic properties of BFAR. In addition, BFAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. BFAR is also thought to be involved in the regulation of neuronal survival.Synonyms: BAR, Bifunctional apoptosis regulator, RING finger protein 47

Gen-ID: 51283

NCBI Accession: NP_057645

UniProt: Q9NZS9