Akirin 1 Antikörper (N-Term)

Produktnummer ABIN499253

Produktdetails anti-Akirin 1 Antikörper

Target: Akirin 1 (AKIRIN1)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Akirin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to AKIRIN1.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Akirin1 antibody was raised against a 16 amino acid peptide near the amino terminus of the human Akirin1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: Akirin1 antibody can be used for detection of Akirin1 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Akirin 1

Target: Akirin 1 (AKIRIN1)

Andere Bezeichnung: AKIRIN1 (AKIRIN1 Produkte)

Synonyme: C1orf108 antikoerper, RP11-781D11.2 antikoerper, STRF2 antikoerper, 6330407G11Rik antikoerper, wu:fa96c11 antikoerper, wu:fc08a11 antikoerper, zgc:64050 antikoerper, AKIRIN1 antikoerper, strf2 antikoerper, akirin 1 antikoerper, akirin 1 S homeolog antikoerper, akirin-1 pseudogene antikoerper, AKIRIN1 antikoerper, Akirin1 antikoerper, akirin1 antikoerper, akirin1.S antikoerper, LOC100316864 antikoerper, LOC100356339 antikoerper

Hintergrund: The highly conserved, nuclear-localized Akirin1 and Akirin2 proteins critically regulate the transcription of NF-kappaB-dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-kappaB pathways. Akirin1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-alpha and IL-1beta signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin mutants show a similar, mid-to-early embryonic death.Synonyms: Akirin-1, C1orf108

Gen-ID: 79647

UniProt: Q9H9L7