XPNPEP1 Antikörper (C-Term)

Produktnummer ABIN499169

Der Ziege Polyklonal anti-XPNPEP1 Antikörper wird verwendet zum Nachweis von XPNPEP1 in Proben von Human, Maus, Ratte, Schwein, Hund und Rind (Kuh). Er wurde validiert für WB.

Kurzübersicht für XPNPEP1 Antikörper (C-Term) (ABIN499169)

Target: XPNPEP1 (X-Prolyl Aminopeptidase (Aminopeptidase P) 1, Soluble (XPNPEP1))

Reaktivität: Human, Maus, Ratte, Schwein, Hund, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser XPNPEP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-XPNPEP1 Antikörper

Bindungsspezifität: C-Term

Sequenz: C-LIRETQPISK QH

Spezifität: This antibody detects XPNPEP1 at C-term. It is expected to recognize isoform 1 and 2 (NP_065116.2, NP_001161076.1).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, rat, cow, pigSpecies reactivity (tested):Human

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the C Terminus of the protein sequence according to NP_065116.2, NP_001161076.1

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: limit dilution 1: 32000. Western blot: 0.3-1 μg/mL. Approx 80 kDa band observed in Human Heart, Skeletal Muscleand Pancreas lysates (calculated MW of 69.0 kDa according to NP_065116.2).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C up to one week or (in aliquots) at -20 °C for longer.

Details zu XPNPEP1

Target: XPNPEP1 (X-Prolyl Aminopeptidase (Aminopeptidase P) 1, Soluble (XPNPEP1))

Andere Bezeichnung: XPNPEP1

Hintergrund: XPNPEP1 is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue. As a result of its specificity toward proline, it has been suggested that XPNPEP1 is important in the maturation and degradation of peptide hormones, neuropeptides, and tachykinins, as well as in the digestion of otherwise resistant dietary protein fragments, thereby complementing the pancreatic peptidases. Deficiency of XPNPEP1 results in excretion of large amounts of imino-oligopeptides in urine.Synonyms: Aminoacylproline aminopeptidase, Cytosolic aminopeptidase P, Soluble aminopeptidase P, X-Pro aminopeptidase 1, X-prolyl aminopeptidase 1 soluble, XPNPEPL, XPNPEPL1, Xaa-Pro aminopeptidase 1

Gen-ID: 7511

NCBI Accession: NP_065116

UniProt: Q9NQW7