SNAP23 Antikörper (Internal Region)

Produktnummer ABIN499144

Dieser Ziege Polyklonal Antikörper detektiert spezifisch SNAP23 in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte und Rind (Kuh).

Kurzübersicht für SNAP23 Antikörper (Internal Region) (ABIN499144)

Target: SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser SNAP23 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-SNAP23 Antikörper

Bindungsspezifität: Internal Region

Sequenz: C-QIKRITDKAD

Spezifität: This antibody is expected to recognize both reported isoforms (NP_003816.2 and NP_570710.1).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Bovine.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_003816.2 and NP_570710.1. Genename: SNAP23

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit Dilution: 1/8000. Western blot: 0.1-0.3 μg/mL. This antibody detects a band of approx. 26 kDa Human Placentalysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu SNAP23

Target: SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))

Andere Bezeichnung: SNAP23

Hintergrund: Synaptosomal-associated proteins (SNAPs) are cytosolic proteins that play a key role in in the process of membrane fusion in intracellular vesicle trafficking. In eukaryotic cells, the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex is critical to membrane docking and fusion and is believed to impart some degree of specificity between vesicle SNARE (v-SNARE) and target organelle SNARE (t-SNARE). In neurons and neuroendocrine cells, the SNARE complex consists of the integral membrane proteins VAMP (vesicle-associated membrane protein), syntaxin and SNAP-25. In non-neuronal tissue, a SNAP-25 homolog, SNAP-23, functionally replaces SNAP-25 in the SNARE complex. Studies show that VAMP, syntaxin and SNAP-23 are required for SNARE function and that this complex exists as a heterotrimer of the three proteins. In insulin signalling pathways, studies suggest that the translocation of GLUT4 in adipocytes requires that functional SNAP-23 be present in SNARE complexes.Synonyms: SNAP-23, Synaptosomal-associated protein 23, Vesicle-membrane fusion protein SNAP-23

Molekulargewicht: 23.4kDa (NP_003816.2

Gen-ID: 8773

NCBI Accession: NP_003816

UniProt: O00161