HOXA1 Antikörper

Produktnummer ABIN499123

Dieser Ziege Polyklonal Antikörper detektiert spezifisch HOXA1 in WB und EIA. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund und Schwein.

Kurzübersicht für HOXA1 Antikörper (ABIN499123)

Target: HOXA1 (Homeobox A1 (HOXA1))

Reaktivität: Human, Maus, Ratte, Hund, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser HOXA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-HOXA1 Antikörper

Spezifität: This antibody is expected to recognize reported isoforms a and b (NP_005513.1 and, NP_705873.2).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Details zu HOXA1

Target: HOXA1 (Homeobox A1 (HOXA1))

Andere Bezeichnung: HOXA1 / HOX1F

Hintergrund: Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxA1 is transcriptionally regulated by retinoic acid (RA) and encodes a transcription factor which has been shown to play important roles in cell differentiation and embryogenesis. HoxA1 is also expressed in cancers, such as mammary tumors, though it is not expressed in normal gland or in precancerous mammary tissues. At embryonic stages, HoxA2 is expressed in the mesenchyme and epithelial cells of the palate, however its expression is restricted to the tips of the growing palatal shelves. HoxA2 protein is predominantly expressed in the nuclei of cells in the ventral mantle region of the developing embryo. In the developing and adult mouse spinal cord, HoxA2 protein may contribute to dorsal-ventral patterning and/or to the specification of neuronal phenotype. HoxA7 functions as a potent transcriptional repressor and its action as such requires several domains, including both activator and repressor regions. HoxA7 is expressed in the fetal liver, lung, skeletal muscle, kidney, pancreas and placenta.Synonyms: Homeobox protein Hox-1F, Homeobox protein Hox-A1

Gen-ID: 3198

NCBI Accession: NP_005513

UniProt: P49639

Pathways: Sensory Perception of Sound