CREB3L1 Antikörper (C-Term)

Produktnummer ABIN499118

Produktdetails anti-CREB3L1 Antikörper

Target: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CREB3L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: C-DFSHSKEWFH DRD

Spezifität: This antibody recognizes OASIS / CREB3L1

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the C Terminus of the protein sequence according to NP_443086.1.

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Detection Limit: 1/32000. Western blot: 1-3 μg/mL. Approx 60 kDa band observed in lysates of cell line A549(calculated MW of 57.0 kDa according to NP_443086.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CREB3L1

Target: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Andere Bezeichnung: CREB3L1 / OASIS (CREB3L1 Produkte)

Synonyme: CREB3L1 antikoerper, OASIS antikoerper, Oasis antikoerper, diacylglycerol kinase-like antikoerper, cAMP responsive element binding protein 3 like 1 antikoerper, cAMP responsive element binding protein 3-like 1 antikoerper, LOC423198 antikoerper, CREB3L1 antikoerper, Creb3l1 antikoerper

Hintergrund: OASIS is a putative CREB/ATF family transcription factor with a putative C-terminal hydrophobic transmembrane domain. It can activate transcription through box-B elements but not through CRE of somatostatin. Shortening of the OASIS transmembrane domain results in a significant increase in transcriptional activity and changes its subcellular localization from the endoplasmic reticulum to the nucleus. The CREB3L1 gene encodes a protein with a transmembrane domain that is a transcriptional activator of the CREB/ATF family.Synonyms: Cyclic AMP-responsive element-binding protein 3-like protein 1, Old astrocyte specifically-induced, PSEC0238, cAMP-responsive element-binding protein 3-like protein 1

Gen-ID: 90993

NCBI Accession: NP_443086

UniProt: Q96BA8

Pathways: Thyroid Hormone Synthesis, Chromatin Binding