MDFI Antikörper

Produktnummer ABIN499093

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MDFI in WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für MDFI Antikörper (ABIN499093)

Target: MDFI (MyoD Family Inhibitor (MDFI))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MDFI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MDFI Antikörper

Spezifität: This antibody detects endogenous levels of MDFI protein. (region surrounding Pro134)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu MDFI

Target: MDFI (MyoD Family Inhibitor (MDFI))

Andere Bezeichnung: MDFI

Hintergrund: MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.Synonyms: MyoD family inhibitor

Molekulargewicht: approx. 25 kDa

Gen-ID: 4188

NCBI Accession: NP_005577

UniProt: Q99750

Pathways: Maintenance of Protein Location