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MDFI Antikörper
MDFI
Reaktivität: Human, Maus
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-MDFI Antikörper
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Target
Alle MDFI Antikörper anzeigen
MDFI
(MyoD Family Inhibitor (MDFI))
Reaktivität
Alle Reaktivitäten für MDFI Antikörper
Human, Maus
Wirt
Alle Wirte für MDFI Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für MDFI Antikörper
Polyklonal
Konjugat
Alle Konjugate für MDFI Antikörper
Dieser MDFI Antikörper ist unkonjugiert
Applikation
Alle Applikationen für MDFI Antikörper
Western Blotting (WB)
Spezifität
This antibody detects endogenous levels of MDFI protein. (region surrounding Pro134)
Kreuzreaktivität (Details)
Species reactivity (expected):Mouse. Species reactivity (tested):Human.
Aufreinigung
Affinity chromatography using epitope-specific immunogen
Reinheit
> 95 % pure by SDS-PAGE
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Applikationshinweise
Western blot: 1: 500 - 1: 1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Details zu MDFI
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Target
MDFI
(MyoD Family Inhibitor (MDFI))
Andere Bezeichnung
MDFI (MDFI Produkte )
Synonyme
MDFI antikoerper, I-MF antikoerper, I-mfa antikoerper, I-mf antikoerper, RGD1560271 antikoerper, MyoD family inhibitor antikoerper, MDFI antikoerper, Mdfi antikoerper
Hintergrund
MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.Synonyms: MyoD family inhibitor
Molekulargewicht
approx. 25 kDa
Gen-ID
4188
NCBI Accession
NP_005577
UniProt
Q99750
Pathways
Maintenance of Protein Location
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