HOXB2 Antikörper

Produktnummer ABIN499088

Der Kaninchen Polyklonal Anti-HOXB2-Antikörper wurde für WB validiert. Er ist geeignet, HOXB2 in Proben von Human zu detektieren.

Kurzübersicht für HOXB2 Antikörper (ABIN499088)

Target: HOXB2 (Homeobox B2 (HOXB2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HOXB2 Antikörper

Spezifität: This antibody detects endogenous levels of HoxB2 protein. (region surrounding Pro67)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu HOXB2

Target: HOXB2 (Homeobox B2 (HOXB2))

Andere Bezeichnung: HOXB2 / HOX2H

Hintergrund: Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxB1 is critical to hindbrain development and has phenotypic features frequently observed in autism. Analysis of expression and targeted disruption of HoxB1 demonstrates that it is also essential for patterning progenitor cells along the entire DV axis of rhombomere 4 (r4). HoxB1 maintains this function by acting very early during hindbrain neurogenesis to specify effectors of the Sonic hedgehog and Mash1 signaling pathways. HoxB2 is a homeodomain protein important in neural development that is also expressed during erythropoiesis, hindbrain development and normal human adult lung development. HoxB2 may modulate the amount of gamma-globin mRNA expressed during development and differentiation. In addition, HoxB2 plays an important role in the patterning of hindbrain and pharyngeal arches in the zebrafish.Synonyms: Homeobox protein Hox-B2, Hox-2.8, Hox-2H, K8

Molekulargewicht: approx. 38 kDa

Gen-ID: 3212

NCBI Accession: NP_002136

UniProt: P14652