GGH Antikörper

Produktnummer ABIN499075

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GGH in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für GGH Antikörper (ABIN499075)

Target: GGH (gamma-Glutamyl Hydrolase (Conjugase, Folylpolygammaglutamyl Hydrolase) (GGH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GGH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GGH Antikörper

Spezifität: This antibody detects endogenous levels of GGH protein. (region surrounding Lys287)

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu GGH

Target: GGH (gamma-Glutamyl Hydrolase (Conjugase, Folylpolygammaglutamyl Hydrolase) (GGH))

Andere Bezeichnung: gamma-Glutamyl Hydrolase / GGH

Hintergrund: GGH (gamma-glutamyl hydrolase), also known as GH or Gamma-Glu-X carboxypeptidase, is a 318 amino acid protein that is secreted into the extracellular space and is also localized to both the lysosome and the melanosome. Functioning as a hydrolase, GGH contains one gamma-glutamyl hydrolase domain through which it catalyzes the hydrolysis of polyglutamate sidechains from pteroylpolyglutamates, specifically hydrolyzing gamma-glutamyl bonds. Via its catalytic activity, GGH may play a role in the bioavailability and metabolic activity of pteroylpolyglutamates. Polymorphisms in the gene encoding GGH are associated with rheumatoid arthritis, inflammatory bowel disease and various cancers.Synonyms: Conjugase, GH, Gamma-Glu-X carboxypeptidase

Molekulargewicht: approx. 36 kDa

Gen-ID: 8836

NCBI Accession: NP_003869

UniProt: Q92820

Pathways: SARS-CoV-2 Protein Interaktom