GABRA6 Antikörper

Produktnummer ABIN499073

Der Kaninchen Polyklonal anti-GABRA6 Antikörper wird verwendet zum Nachweis von GABRA6 in Proben von Human, Ratte und Maus. Er wurde validiert für WB.

Kurzübersicht für GABRA6 Antikörper (ABIN499073)

Target: GABRA6 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 6 (GABRA6))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABRA6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GABRA6 Antikörper

Spezifität: This antibody detects endogenous levels of GABAA Rα6 protein. (region surrounding Pro97)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu GABRA6

Target: GABRA6 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 6 (GABRA6))

Andere Bezeichnung: GABAA Receptor alpha 6

Hintergrund: GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Rα1-6, GABAA R β1-3, GABAA R gamma1-3, GABAA R delta, GABAA Ré, GABAA R rho1 and GABAA R roh2. The GABAB family is composed of GABAB R1α and GABAB R1β. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.Synonyms: GABRA-6, GABRA6, Gamma-Aminobutyric Acid Receptor subunit Alpha-6

Molekulargewicht: approx. 51 kDa

Gen-ID: 2559

NCBI Accession: NP_000802

UniProt: Q16445

Pathways: Synaptic Membrane