CD69 Antikörper

Produktnummer ABIN499066

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CD69 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für CD69 Antikörper (ABIN499066)

Target: CD69

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD69 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD69 Antikörper

Spezifität: This antibody detects endogenous levels of CD69 protein. (region surrounding Arg134)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CD69

Target: CD69

Andere Bezeichnung: CD69

Hintergrund: CD69 is a disulfide linked transmembrane homodimer whose differentially glycosylated subunits range from 35-39 kDa. It is a C type lectin, most closely related to the NKRP1 and Ly49 NK cell activation molecules. CD69 is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. It is the earliest inducible cell surface glycoprotein acquired during lymphoid activation. Induction occurs by antigens, mitogens or activators of PKC on the surface of T and B lymphocytes, and by interaction of IL2 with the p75 IL2R on the surface of NK cells. Constitutive expression of CD69 on subsets of thymocytes suggests that it may be involved in regulation of developmental events in addition to its role in activation of a variety of hematopoietic cells.Synonyms: AIM, Activation inducer molecule, BL-AC/P26, C-type lectin domain family 2 member C, EA1, Early T-cell activation antigen p60, Early activation antigen CD69, GP32/28, Leu-23, MLR-3

Molekulargewicht: approx. 23 kDa

Gen-ID: 969

NCBI Accession: NP_001772

UniProt: Q07108