L1CAM Antikörper

Produktnummer ABIN498991

Produktdetails anti-L1CAM Antikörper

Target: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser L1CAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of NCAM-L1 protein. AP21093PU-N binds to the cytoplasmic region of NCAM-L1.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate Buffered Saline (PBS), pH ~7.2, 15 mM Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu L1CAM

Target: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Andere Bezeichnung: CD171 / L1CAM (L1CAM Produkte)

Synonyme: l1cam-a antikoerper, CAML1 antikoerper, CD171 antikoerper, HSAS antikoerper, HSAS1 antikoerper, MASA antikoerper, MIC5 antikoerper, N-CAM-L1 antikoerper, N-CAML1 antikoerper, NCAM-L1 antikoerper, S10 antikoerper, SPG1 antikoerper, L1 antikoerper, Hsas antikoerper, Hyd antikoerper, NCAML1 antikoerper, L1 cell adhesion molecule S homeolog antikoerper, L1 cell adhesion molecule antikoerper, l1cam.S antikoerper, L1CAM antikoerper, L1cam antikoerper

Hintergrund: The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius), 2) MASA (mental retardation, aphasia, shuffling gait, adductus thumbs), and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, neural migration and in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm.Synonyms: CAML1, MIC5, N-CAM L1, Neural cell adhesion molecule L1

Molekulargewicht: approx. 140 kDa

Gen-ID: 3897

NCBI Accession: NP_000416

UniProt: P32004

Pathways: Synaptic Membrane