×
Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.
GATA1 Antikörper (pSer310)
GATA1
Reaktivität: Human, Maus, Ratte
IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-GATA1 Antikörper
(ausblenden)
Target
Alle GATA1 Antikörper anzeigen
GATA1
(GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))
Bindungsspezifität
Alle Epitope für GATA1 Antikörper
pSer310
Reaktivität
Alle Reaktivitäten für GATA1 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für GATA1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für GATA1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für GATA1 Antikörper
Dieser GATA1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für GATA1 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
This antibody detects endogenous levels of p-GATA-1 protein only when phosphorylated at Ser310.
Kreuzreaktivität (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Aufreinigung
Affinity chromatography
Reinheit
> 95 % by SDS-PAGE
Top Product
Discover our top product GATA1 Primärantikörper
Alternativen
(anzeigen)
Anwendungsinformationen
(ausblenden)
Applikationshinweise
Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
(ausblenden)
Konzentration
1,0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu GATA1
(ausblenden)
Target
GATA1
(GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))
Andere Bezeichnung
GATA1 (GATA1 Produkte )
Synonyme
ERYF1 antikoerper, GATA-1 antikoerper, GF-1 antikoerper, GF1 antikoerper, NF-E1 antikoerper, NFE1 antikoerper, XLANP antikoerper, XLTDA antikoerper, XLTT antikoerper, Gata-1 antikoerper, Gf-1 antikoerper, eryf1 antikoerper, Eryf1 antikoerper, GATA1 antikoerper, gata-1 antikoerper, Gata1 antikoerper, si:dkeyp-77f7.5 antikoerper, gata1 antikoerper, gata1a-A antikoerper, xGATA-1 antikoerper, xgata1 antikoerper, XGATA-1B antikoerper, gata1b-A antikoerper, gta1 antikoerper, zg1 antikoerper, NF-E1a antikoerper, GATA binding protein 1 antikoerper, GATA binding protein 1 (globin transcription factor 1) antikoerper, amidase antikoerper, aspartyl/glutamyl-tRNA amidotransferase subunit A antikoerper, putative amidase antikoerper, GatA1 antikoerper, glutamyl-tRNA amidotransferase subunit A antikoerper, hematopietic transcription factor GATA-1 antikoerper, GATA binding protein 1b antikoerper, GATA binding protein 1 L homeolog antikoerper, GATA binding protein 1 S homeolog antikoerper, GATA binding protein 1a antikoerper, erythroid transcription factor antikoerper, GATA1 antikoerper, Gata1 antikoerper, gatA1 antikoerper, gata-1 antikoerper, gata1b antikoerper, gata1.L antikoerper, gata1.S antikoerper, gata1a antikoerper, LOC108348091 antikoerper
Hintergrund
GATA1 (Globin transcription factor 1) is a Cys2/Cys2 zinc finger DNA binding protein that is expressed primarily in erythroid, megakaryocytic, mast cells and eosinophilic cells. It belongs to the GATA family of transcription factors. GATA1 is a transcriptional activator which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence [AT]GATA[AG] within regulatory regions of globin genes and of other genes expressed in erythroid cells. The protein also plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. Acquired somatic mutations in GATA1 occur in virtually all children with Down's Syndrome, congenital transient myeloproliferative syndrome (TMD) and acute megakaryocytic leukemia.Synonyms: ERYF1, Eryf1, Erythroid transcription factor, GATA-1, GATA-binding factor 1, GF-1, GF1, NF-E1 DNA-binding protein
Molekulargewicht
approx. 43 kDa
Gen-ID
2623
NCBI Accession
NP_002040
UniProt
P15976
Pathways
Cellular Response to Molecule of Bacterial Origin
Zuletzt angesehen
(ausblenden)