GAP43 Antikörper (pSer41)

Produktnummer ABIN498764

Der Kaninchen Polyklonal anti-GAP43 Antikörper wird verwendet zum Nachweis von GAP43 in Proben von Human, Ratte und Maus. Er wurde validiert für IF.

Kurzübersicht für GAP43 Antikörper (pSer41) (ABIN498764)

Target: GAP43 (Growth Associated Protein 43 (GAP43))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GAP43 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Produktdetails anti-GAP43 Antikörper

Bindungsspezifität: pSer41

Spezifität: This antibodiy detects endogenous levels of GAP43 protein only when phosphorylated at Ser41.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GAP43

Target: GAP43 (Growth Associated Protein 43 (GAP43))

Andere Bezeichnung: GAP43

Hintergrund: GAP-43 (growth associated protein 43, B-50, PP46, calmodulin-binding protein P-57, neuromodulin, neuron growth-associated protein 43, protein F1 is a crucial component for regenerative response in the nervous system. It is present at high levels in neuronal growth cones during development and axonal regeneration. GAP-43 is normally produced by neurons during developmental growth and axonal regeneration, but it is also expressed in specific regions of the normal adult nervous system. The neuron-specific Elav/Hu family member, HuD, interacts with and stabilizes GAP-43 mRNA in developing neurons and leads to increased levels of GAP-43 protein.Synonyms: Axonal membrane protein GAP-43, Growth-associated protein 43, Neural phosphoprotein B-50, Neuromodulin, PP46

Molekulargewicht: approx. 38, 43 kDa

Gen-ID: 2596

NCBI Accession: NP_002036

UniProt: P17677