PGC
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
PEPC antikoerper, PGII antikoerper, 2210410L06Rik antikoerper, Upg-1 antikoerper, Upg1 antikoerper, CPGC antikoerper, gastricsin antikoerper, PG1 antikoerper, Pg-1 antikoerper, PGNC antikoerper, PGC antikoerper, Gastricsin antikoerper, progastricsin (pepsinogen C) antikoerper, progastricsin antikoerper, PGC antikoerper, Pgc antikoerper
Hintergrund
Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, Pepsinogen, by removal of a 41 amino acid segment from the amino end. Pepsinogen is synthesized in the stomach lining, hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity ( pH 1-3) for Pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. It shows extremely broad specificity, and although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. The amino acid composition of Pepsin C differs from those of Pepsinogen and Pepsin, especially in the content of basic amino acids, glutamic acid, aspartic acid, leucine and isoleucine.Synonyms: Gastricsin, PGC, Pepsinogen C, Progastricsin