DEFA4 Antikörper

Produktnummer ABIN498518

Der Kaninchen Polyklonal Anti-DEFA4-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, DEFA4 in Proben von Human zu detektieren.

Kurzübersicht für DEFA4 Antikörper (ABIN498518)

Target: DEFA4 (Defensin, alpha 4, Corticostatin (DEFA4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DEFA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DEFA4 Antikörper

Spezifität: This antibody detects endogenous levels of Defensin α4 protein. (region surrounding Asp27)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu DEFA4

Target: DEFA4 (Defensin, alpha 4, Corticostatin (DEFA4))

Andere Bezeichnung: Defensin alpha 4

Hintergrund: Human neutrophil alpha-defensins (also designated HNPs) are small, cationic, cysteine-rich antimicrobial proteins that play important roles in innate immunity against infectious microbes such as bacteri,a fungi and enveloped viruses. Alpha-defensins are synthesized as inactive precursors and are activated by proteolytic cleavage by MMP-7. Paneth cells in small intestinal crypts secrete the alpha-defensins, which are also termed cryptidins in mice. The cryptidin-4 gene is unique among the Paneth cell alpha defensins in that it is inactive in the duodenum, but expressed at maximal levels in the distal small bowel.Synonyms: DEF4, DEFA4, HNP-4, HP-4, Neutrophil defensin 4

Molekulargewicht: approx. 11 kDa

Gen-ID: 1669

NCBI Accession: NP_001916

UniProt: P12838