BCL2L2 Antikörper

Produktnummer ABIN498448

Produktdetails anti-BCL2L2 Antikörper

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL2L2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of Bcl-w protein. (region surrounding Gly154)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu BCL2L2

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Andere Bezeichnung: Bcl-2-Like 2 (BCL2L2 Produkte)

Synonyme: bcl2l2 antikoerper, BCL2L2 antikoerper, BCL-W antikoerper, BCL2-L-2 antikoerper, BCLW antikoerper, PPP1R51 antikoerper, AW048834 antikoerper, Bcl-w antikoerper, Gtrgal2 antikoerper, Gtrosa41 antikoerper, bclw antikoerper, c98 antikoerper, BCL-WEL antikoerper, BCL-WS antikoerper, Bclw antikoerper, bcl-w antikoerper, bcl2l2-a antikoerper, bcl2l2-b antikoerper, xr1 antikoerper, BCL2 like 2 antikoerper, BCL2-like 2 antikoerper, BCL2 like 12 antikoerper, Bcl2-like 2 antikoerper, bcl-2-like protein 2 antikoerper, BCL2-like 2 L homeolog antikoerper, BCL2L2 antikoerper, bcl2l2 antikoerper, BCL2L12 antikoerper, Bcl2l2 antikoerper, LOC100154044 antikoerper, LOC100345100 antikoerper, bcl2l2.L antikoerper

Hintergrund: The Bcl-2 family of proteins is characterized by its ability to modulate cell death (apoptosis) under a broad range of physiological conditions. Bcl-2, A1 and Bcl-xL function to inhibit apoptosis while other members of the Bcl-2 family, Bax, Bad, Bak and Bcl-xS oppose their death-suppressing effects. Using a PCR-based strategy, an additional protein with life-promoting activity, designated Bcl-w, has been identified. The protein is highly conserved between mouse and human and is encoded by a gene located near the TCRalpha gene on chromosome 14. Bcl-w is expressed in myeloid cell lines but not in T and B lymphocytes, and can be found in a wide range of tissues. An alternative splicing event in exon 4 results in two transcripts. The first, Bcl-w, encodes a protein of 193 amino acids, and the second, Bcl-w/rox, encodes a protein 333 amino acids in length. The Synonyms: BCL2L2, BCLW, Bcl-w, Bcl2-L-2, KIAA0271

Molekulargewicht: approx. 21 kDa

Gen-ID: 599

NCBI Accession: NP_004041

UniProt: Q92843