ADD2 Antikörper

Produktnummer ABIN498443

Der Kaninchen Polyklonal anti-ADD2 Antikörper wird verwendet zum Nachweis von ADD2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und IF.

Kurzübersicht für ADD2 Antikörper (ABIN498443)

Target: ADD2 (Adducin 2 (Beta) (ADD2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-ADD2 Antikörper

Spezifität: This antibody detects endogenous levels of Adducin beta protein.(region surrounding Glu497)

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ADD2

Target: ADD2 (Adducin 2 (Beta) (ADD2))

Andere Bezeichnung: beta-Adducin (ADD2)

Hintergrund: Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta and gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and adducins are central in the cortical actin network organization. Adducin alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin alpha and Adducin gamma is ubiquitous in contrast to the restricted expression of Adducin beta. Adducin beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow in humans, and spleen in mice.Synonyms: ADDB, Adducin 2, Erythrocyte adducin subunit beta

Molekulargewicht: approx. 81 kDa

Gen-ID: 119

NCBI Accession: NP_001608

UniProt: P35612

Pathways: Regulation of Actin Filament Polymerization