RBM5 Antikörper

Produktnummer ABIN498423

Der Kaninchen Polyklonal anti-RBM5 Antikörper (ABIN498423) detektiert spezifisch RBM5 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für RBM5 Antikörper (ABIN498423)

Target: RBM5 (RNA Binding Motif Protein 5 (RBM5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBM5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RBM5 Antikörper

Spezifität: This antibody detects endogenous levels of LUCA15 protein. (region surrounding asn261)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RBM5

Target: RBM5 (RNA Binding Motif Protein 5 (RBM5))

Andere Bezeichnung: RBM5 / LUCA15

Hintergrund: DEF-3 and LUCA15 belong to an evolutionarily conserved family of RNA binding proteins and share similiar expression patterns. Both DEF-3 and LUCA15 are highly expressed in adult heart and thymus as well as fetal kidney. Conversely, fetal thymus and adult kidney express very little DEF-3 and LUCA15. In the haemopoietic system of mice, the expression of DEF-3 is downregulated upon differentiation of progenitor cells into granulocytes but persists during macrophage development. Both DEF-3 and LUCA15 contain two zinc finger motifs, a bipartite nuclear signal and two RNA binding motifs. DEF-3 and LUCA15 are capable of specifically binding poly(G) RNA.Synonyms: NY-REN-9, Putative tumor suppressor LUCA15, RNA-binding motif protein 5, RNA-binding protein 5, Renal carcinoma antigen NY-REN-9

Molekulargewicht: approx. 92 kDa

Gen-ID: 10181

NCBI Accession: NP_005769

UniProt: P52756

Pathways: Ribonucleoprotein Complex Subunit Organization