RBMX Antikörper

Produktnummer ABIN498314

Der Kaninchen Polyklonal anti-RBMX Antikörper wird verwendet zum Nachweis von RBMX in Proben von Human, Ratte und Maus. Er wurde validiert für WB, IF und IHC (p).

Kurzübersicht für RBMX Antikörper (ABIN498314)

Target: RBMX (RNA Binding Motif Protein, X-Linked (RBMX))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBMX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RBMX Antikörper

Spezifität: This antibody detects endogenous levels of hnRNP G protein. (region surrounding Met40)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity-Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RBMX

Target: RBMX (RNA Binding Motif Protein, X-Linked (RBMX))

Andere Bezeichnung: RBMX / HNRPG

Hintergrund: Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to mRNA transcription, pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. There are approximately 20 known hnRNP proteins, and their complexes are the major constituents of the spliceosome. The majority of hnRNP proteins components are localized to the nucleus, however some shuttle between the nucleus and the cytoplasm. hnRNP G is a glycoprotein, which was originally identified as an autoantigen from German shepherd dogs with lupus-like syndrome. The gene encoding hnRNP G is located on chromosome Xq26 and is ubiquitously expressed. It contains one RNP-consensus RNA binding domain (RBD) and is related to RBMY, which is involved in spermatogenesis, and hnRNP G-T, which is a testis specific protein. All three proteins interact with Tra2b and therefore, are involved in pre-mRNA splicing.Synonyms: Glycoprotein p43, Heterogeneous nuclear ribonucleoprotein G, RBMXP1, RNA-binding motif protein X chromosome, hnRNP G

Molekulargewicht: approx. 40 kDa

Gen-ID: 27316

NCBI Accession: NP_002130

UniProt: P38159

Pathways: Chromatin Binding, Ribonucleoprotein Complex Subunit Organization