SKIL Antikörper

Produktnummer ABIN498307

Produktdetails anti-SKIL Antikörper

Target: SKIL (SKI-Like Oncogene (SKIL))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SKIL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of SnoN protein. (region surrounding Asp652)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu SKIL

Target: SKIL (SKI-Like Oncogene (SKIL))

Andere Bezeichnung: SKIL / SnoN (SKIL Produkte)

Synonyme: SNO antikoerper, SnoA antikoerper, SnoI antikoerper, SnoN antikoerper, Skir antikoerper, Sno antikoerper, SKIL antikoerper, DKFZp459L122 antikoerper, sno antikoerper, zgc:193698 antikoerper, SKI like proto-oncogene antikoerper, SKI-like proto-oncogene antikoerper, ski-like protein antikoerper, SKI-like antikoerper, SKI-like proto-oncogene b antikoerper, SKIL antikoerper, Skil antikoerper, LOC100010058 antikoerper, skil antikoerper, skilb antikoerper

Hintergrund: SnoN may have a regulatory role in cell division or differentiation in response to extracellular signals. SnoN acts as a positive mediator of TGF beta induced transcription and cell cycle arrest in lung epithelial cells. The ability of SnoN to repress the growth inhibitory function of the Smad proteins is required for their transforming activity.Synonyms: SNO, Ski-like protein, Ski-related novel protein N, Ski-related oncogene, Ski-related protein, SnoA, Snol

Molekulargewicht: approx. 77 kDa

Gen-ID: 6498

NCBI Accession: NP_001138569

UniProt: P12757

Pathways: Positive Regulation of Response to DNA Damage Stimulus