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beta 2 Adrenergic Receptor Antikörper

ADRB2 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN498188
  • Target Alle beta 2 Adrenergic Receptor (ADRB2) Antikörper anzeigen
    beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
    Reaktivität
    • 151
    • 78
    • 69
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 149
    • 10
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 137
    • 24
    • 2
    Polyklonal
    Konjugat
    • 85
    • 12
    • 10
    • 10
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser beta 2 Adrenergic Receptor Antikörper ist unkonjugiert
    Applikation
    • 111
    • 72
    • 49
    • 41
    • 27
    • 26
    • 26
    • 22
    • 15
    • 13
    • 10
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody detects endogenous levels of AR-β2 protein.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography using epitope-specific immunogen
    Reinheit
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product ADRB2 Primärantikörper
  • Applikationshinweise
    Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Müller, Schwab, Rosenfeld, Antonow-Schlorke, Nathanielsz, Rakers, Schubert, Witte, Rupprecht: "Fetal Sheep Mesenteric Resistance Arteries: Functional and Structural Maturation." in: Journal of vascular research, Vol. 54, Issue 5, pp. 259-271, (2017) (PubMed).

  • Target
    beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
    Andere Bezeichnung
    beta-2 Adrenergic Receptor (ADRB2 Produkte)
    Synonyme
    zgc:162188 antikoerper, adrb2 antikoerper, Adrb-2 antikoerper, Badm antikoerper, Gpcr7 antikoerper, ADRB2R antikoerper, ADRBR antikoerper, B2AR antikoerper, BAR antikoerper, BETA2AR antikoerper, adrenoceptor beta 2 antikoerper, adrenoceptor beta 2, surface b antikoerper, beta2-adrenergic receptor antikoerper, adrenergic receptor, beta 2 antikoerper, ADRB2 antikoerper, adrb2b antikoerper, LOC100136153 antikoerper, Adrb2 antikoerper
    Hintergrund
    Beta 2 Adrenergic Receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthm,a obesity and type 2 diabetes. Expression of the beta 2 Adrenergic Receptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel.Synonyms: ADRB2, ADRB2R, B2AR, Beta-2 adrenoreceptor
    Molekulargewicht
    approx. 47 kDa
    Gen-ID
    154
    NCBI Accession
    NP_000015
    UniProt
    P07550
    Pathways
    cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
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