PMP22 Antikörper

Produktnummer ABIN498164

Der Kaninchen Polyklonal anti-PMP22 Antikörper wird verwendet zum Nachweis von PMP22 in Proben von Human, Ratte und Maus. Er wurde validiert für WB und IHC (p).

Kurzübersicht für PMP22 Antikörper (ABIN498164)

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PMP22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PMP22 Antikörper

Spezifität: This detects endogenous levels of GAS3 protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000. immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu PMP22

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Andere Bezeichnung: PMP22

Hintergrund: PMP 22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.Synonyms: GAS-3, GAS3, Growth arrest-specific protein 3, PMP-22, Peripheral myelin protein 22

Molekulargewicht: approx. 22 kDa

Gen-ID: 5376

NCBI Accession: NP_000295

UniProt: Q01453