RACGAP1 Antikörper

Produktnummer ABIN498154

Produktdetails anti-RACGAP1 Antikörper

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RACGAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of MgcRacGAP protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu RACGAP1

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Andere Bezeichnung: RACGAP1 (RACGAP1 Produkte)

Synonyme: CYK4 antikoerper, HsCYK-4 antikoerper, ID-GAP antikoerper, MgcRacGAP antikoerper, cyk-4 antikoerper, id-gap antikoerper, mgcracgap antikoerper, RACGAP1 antikoerper, MGC121578 antikoerper, Gap antikoerper, RasGAP antikoerper, Rasa antikoerper, GAPX antikoerper, AI227039 antikoerper, AI327394 antikoerper, Band25 antikoerper, GTPase antikoerper, gtl11 antikoerper, mKIAA1478 antikoerper, wu:fb92c08 antikoerper, zgc:77839 antikoerper, Rac GTPase activating protein 1 antikoerper, rac GTPase-activating protein 1 antikoerper, Rac GTPase activating protein 1 L homeolog antikoerper, RAS p21 protein activator 1 antikoerper, Rac GTPase-activating protein 1 antikoerper, si:ch1073-416j23.1 antikoerper, RACGAP1 antikoerper, racgap1 antikoerper, racgap1.L antikoerper, racgap1.2.L antikoerper, racgap1.2 antikoerper, Rasa1 antikoerper, Racgap1 antikoerper, si:ch1073-416j23.1 antikoerper

Hintergrund: Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.Synonyms: KIAA1478, MGCRACGAP, Male germ cell RacGap, Rac GTPase-activating protein 1

Molekulargewicht: approx. 72 kDa

Gen-ID: 29127

NCBI Accession: NP_001119575

UniProt: Q9H0H5

Pathways: Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor