GRIN3B Antikörper (C-Term)

Produktnummer ABIN498089

Der Ziege Polyklonal anti-GRIN3B Antikörper wird verwendet zum Nachweis von GRIN3B in Proben von Human. Er wurde validiert für WB und EIA.

Kurzübersicht für GRIN3B Antikörper (C-Term) (ABIN498089)

Target: GRIN3B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 3B (GRIN3B))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GRIN3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-GRIN3B Antikörper

Bindungsspezifität: C-Term

Sequenz: C-EAPPHSGRPG SQ

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the C Terminus of the protein sequence according to NP_619635.1. Genename: GRIN3B

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Detection Limit: 1/8000. Western blot: 0.5-1.5 μg/mL. Detects a band of Approx 110 kDa in Human Brain (Cerebellum and Cerebral Cortex) lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Species Reactivity: Tested: Human. Add. Information: Calculated Molecular Weight: 110 kDa according to NP_619635.1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GRIN3B

Target: GRIN3B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 3B (GRIN3B))

Andere Bezeichnung: GRIN3B

Hintergrund: NR3B is a NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. NR3B is found in a complex containing GRIN1 and GRIN2A at the cell membrane. NR3B requires the presence of GRIN1 to be targeted at the cell membrane. NR3B is expressed in the hippocampus, corpus callosum, as well as the facial and trigeminal nuclei of the brainstem and the ventral horn of the spinal cord.Synonyms: Glutamate [NMDA] receptor subunit 3B, NMDAR3B, NR3B

Gen-ID: 116444

NCBI Accession: NP_619635

UniProt: O60391