HOXA4 Antikörper (Internal Region)

Produktnummer ABIN498071

Der Ziege Polyklonal Anti-HOXA4-Antikörper wurde für WB und EIA validiert. Er ist geeignet, HOXA4 in Proben von Human und Hund zu detektieren.

Kurzübersicht für HOXA4 Antikörper (Internal Region) (ABIN498071)

Target: HOXA4 (Homeobox A4 (HOXA4))

Reaktivität: Human, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser HOXA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-HOXA4 Antikörper

Bindungsspezifität: Internal Region

Sequenz: C-QAKGPAHGLH ASH

Spezifität: Recognizes HOXA4.

Kreuzreaktivität (Details): Species reactivity (expected):Canine (Dog).
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_002132.3. Genename: HOXA4

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Detection Limit: 1/32000. Western blot: 0.1-0.3 μg/mL. Detects a band of Approx 36 kDa in Human Colon lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu HOXA4

Target: HOXA4 (Homeobox A4 (HOXA4))

Andere Bezeichnung: HOXA4 / HOX1D

Hintergrund: The Hox homeobox genes encode proteins that are transcriptional regulators with an established role in embryonic development. HoxA4 (homeobox A4), also known as HOX1D or HOX1, is a 320 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Expressed in the embryonic nervous system, HoxA4 functions as a sequence-specific DNA-binding transcription factor that is part of a regulatory mechanism that provides cells with positional identities during development. Via its ability to bind DNA, HoxA4 plays an important role in the regulation of gene expression, as well as morphogenesis and differentiation. The gene encoding HoxA4 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5 % of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome.Synonyms: Homeobox protein Hox-A4, Hox-1.4, Hox-1D

Gen-ID: 3201

NCBI Accession: NP_002132

UniProt: Q00056