MON1A Antikörper (Internal Region)

Produktnummer ABIN498066

Dieses Anti-MON1A-Antikörper ist ein Ziege Polyklonal-Antikörper zur Detektion von MON1A in WB und EIA. Geeignet für Human, Maus, Ratte, Rind (Kuh) und Hund.

Kurzübersicht für MON1A Antikörper (Internal Region) (ABIN498066)

Target: MON1A (MON1 Homolog A (MON1A))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser MON1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-MON1A Antikörper

Bindungsspezifität: AA 589-601, Internal Region

Sequenz: C-RPLKTIYYTG PNE

Spezifität: This antibody is expected to recognize isoforms a and b (NP_115731.2, NP_001135973.1).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog), Bovine.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_115731.2, NP_001135973.1. Genename: MON1A

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Detection Limit: 1/8000. Western blot: 1-3 μg/mL. Detects a band of Approx 50 kDa in lysates of cell line Jurkat.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu MON1A

Target: MON1A (MON1 Homolog A (MON1A))

Andere Bezeichnung: MON1A

Hintergrund: MON1A also known as SAND1, is a 555 amino acid protein that exists as multiple alternatively spliced isoforms and plays an important role in membrane trafficking, specifically through the secretory apparatus. The gene encoding MON1A maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene clusterand a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.Synonyms: SAND1, Vacuolar fusion protein MON1 homolog A

Gen-ID: 84315

NCBI Accession: NP_001135973

UniProt: Q86VX9

Pathways: Transition Metal Ion Homeostasis