JUP Antikörper (N-Term)
Kurzübersicht für JUP Antikörper (N-Term) (ABIN4956513)
Target
Alle JUP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 5-21, N-Term
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Kreuzreaktivität
- Human, Maus
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Immunogen
- synthetic N-terminus of human plakoglobin (aa 5-21)
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Applikationshinweise
- Dilution for IHC: 1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- serum
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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- JUP (Junction Plakoglobin (JUP))
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Andere Bezeichnung
- plakoglobin
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Hintergrund
- Specific detection of Mr 83 000 Plakoglobin, "band 5" polypeptide of intercellular adhering junctions (also described as γ-catenin). Excellent marker for all forms of intercellular adhering junctions, such as: desmosomes of epithelial and myocardial cells (incl. cultured cells), zonulae and fasciae adherentes of epithelia, endothelia of blood vessels and myocardial cells, adherens-type junctions (e.g. lens tissue, pigmented retinal cells, Sertoli cells of testis). Especially useful for studying plakoglobin mutations in cardiomyopathies (e.g. ARVC)
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Pathways
- Cell-Cell Junction Organization, Maintenance of Protein Location
Target
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