Complement C3b Alpha' Chain Antikörper

Produktnummer ABIN4956351

Produktdetails

Target: Complement C3b Alpha' Chain

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: purified

Immunogen: human complement component C3

Klon: H206

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Dilution for IHC: 1:10

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with 1 mL deionized water

Buffer: PBS, pH 7.22

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Antigendetails

Target: Complement C3b Alpha' Chain

Andere Bezeichnung: C3b-alpha

Hintergrund: H 206 allows demonstration of C3 deposits in tissue, on cells, on microorganisms and in immune complexes. It does not react with C3a or C3d and does not inhibit hemolytic function of C3. The epitope was located on the C-termius of the alpha-chain (39.5 kD fragment of C3c). Detection of C3b deposits in tissue, on cells, on microorganisms and in immune complexes. It should be used with positive control anti C3b-ß, (H11, Cat. No. 61020) and negative control anti-C3a (H13, Cat. No. 61018). Activated, deposited C3b bears C3b-α and C3b-ß, but no longer C3a. Ubiquitous or nonspecifically absorbed C3 is still C3a positive with H 13.