TOR2A Antikörper (AA 194-221)

Produktnummer ABIN3029188

Produktdetails anti-TOR2A Antikörper

Target: TOR2A (Torsin Family 2, Member A (TOR2A))

Bindungsspezifität: AA 194-221

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOR2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität (Details): Expected species reactivity: Rat

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 194-221 from the human protein was used as the immunogen for this TOR2A antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the TOR2A antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the TOR2A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu TOR2A

Target: TOR2A (Torsin Family 2, Member A (TOR2A))

Andere Bezeichnung: TOR2A (TOR2A Produkte)

Synonyme: tor2a antikoerper, TOR2A antikoerper, zgc:114110 antikoerper, TORP1 antikoerper, Prosalusin antikoerper, Torsin-2A antikoerper, torsin family 2 member A antikoerper, torsin family 2, member A L homeolog antikoerper, torsin family 2, member A antikoerper, TOR2A antikoerper, tor2a.L antikoerper, tor2a antikoerper, Tor2a antikoerper

Hintergrund: Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids. Salusin alpha has recently been shown to be involved in atherosclerosis, it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation.

UniProt: Q5JU69